Junk DNA, Nessa Carey
Junk DNA, Nessa Carey
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Junk DNA
A Journey Through the Dark Matter of the Genome

Author: Nessa Carey

Narrator: Cat Gould

Unabridged: 10 hr 16 min

Format: Digital Audiobook Download

Publisher: Tantor Media

Published: 06/23/2020


Synopsis

For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases.

Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field.

About Nessa Carey

Nessa Carey has a virology PhD from the University of Edinburgh and is a former senior lecturer in molecular biology at Imperial College, London. She worked in the biotech and pharmaceutical industry for thirteen years and is now International Director for the UK's leading organization for technology transfer professionals. She lives in Norfolk and is a visiting professor at Imperial College.


Reviews

Goodreads review by Jamie on May 03, 2022

I studied the C programming language, and one of the things that was stressed was the danger of null pointers. A pointer is a type of variable that points directly to a location in memory, so it is a fast and efficient way to access data. However, when you create one, if you forget to set it to an i......more

Goodreads review by J.M. on November 24, 2015

A self-explanatory title, but not quite: the object of this book is to reveal the many ways in which so called “junk” DNA is nothing of the sort. About 98% of human DNA does not code for protein production, and this has traditionally been assigned the status of junk. But there are many ways in which......more

Goodreads review by Nicky on April 09, 2016

I’ve read Nessa Carey’s work before, in The Epigenetics Revolution, so I had high hopes for this — especially because it involves a lot more discussion of epigenetic modification of gene expression, and because genetics in general is something that fascinates me. If this is an interest of yours, the......more

Goodreads review by Orla on August 26, 2024

6/5. maybe the best biology book i’ve ever read?? any interesting topic around genetics that i could think of was included. X-inactivation, telomeres and aging, etc etc etc. will it take me the rest of the year to truly understand what’s going on ? yeah probably. but still 6/5⭐️⭐️⭐️⭐️⭐️⭐️......more

Goodreads review by Charlene on February 28, 2016

Great examination of just what "junk" DNA can do. When humans don't understand something, they often label it in such a way to suggest it does not matter. Labeling the non-coding portion of DNA as "junk" is just such a case. Carey provides the reader with myriad evidence about the wonderful role jun......more